Time
Module
Activity
Room, Location
Teacher
Content
w3, 2023 
Monday2023-01-16 09:00 - 09:30 3MB031
3MB031
5MO120
5MO120
Mandatory
Roll-call/Introduction
6K Thymine
6L Uracil
Changchun Chen Schedule may be subject to change

Course leader: Changchun Chen
changchun.chen@umu.se

Introduction to the course (CC)
09:30 - 14:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Task
6K Thymine
6L Uracil
Changchun Chen
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Lecture: Genetic nomenclature, mutations and their isolation and selection (VS) and Problem-solving class 1 (PSC 1) (CC, KV, YÖ)
Tuesday2023-01-17 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Task
6K Thymine
6L Uracil
Anders Byström “The concept of suppression” and PSC 2 (AB)
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Question time
6K Thymine
6L Uracil
Vicky Shingler Lecture: Prokaryotic gene structure and regulation: the use of transcription versus
translational fusions (VS) and PSC 3 (questions only)
Wednesday2023-01-18 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Question time
6K Thymine
6L Uracil
Vicky Shingler Lecture: From restriction enzymes to simple cloning (VS) and PSC 4 (questions only)
Thursday2023-01-19 09:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Task
6K Thymine
6L Uracil
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Lecture (MGA): Genetic analysis of a transcriptional regulator (VS). With introduction to Experiment 1: Isolation and mapping of a suppressor mutation in E. coli. Pre-lab Experiment 1 - Tasks 1 and 2 (VS, KV, YÖ)
13:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Task
6K Thymine
6L Uracil
Katarina Vielfort
Yngve Östberg
Exercise 1: Analysis of DNA and protein sequences (KV, YÖ)
Friday2023-01-20 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6K Thymine
6L Uracil
Katarina Vielfort
Yngve Östberg
Wet lab information (lab safety etc) – Introduction to Experiment 1 - Task 3 (KV, YÖ)
10:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Gröna labbet
6L Gröna labbet annex
6L Röda labbet
6L Röda labbet annex
Experiment 1 - Task 3 continued
w4, 2023 
Monday2023-01-23 09:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Task
6K Thymine
6L Uracil
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Lecture: Classical mutation mapping in bacteria-phage transduction and HFR (VS) and PSC 5 (VS, KV, YÖ)
13:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Experiment 1 - Task 3
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline answers to PSC3 and PSC4 (up-load on Canvas).
Tuesday2023-01-24 08:00 - 09:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Experiment 1 - Task 3
09:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6K Thymine
6L Uracil
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Pre-lab Experiment 1 – Task 4 (VS, KV, YÖ)
12:00 - 12:15 3MB031
3MB031
5MO120
5MO120
Information Free afternoon for Uniaden (08:00 - 16:00, Universum)
Thursday2023-01-26 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6K Thymine
6L Uracil
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Pre-lab Experiment 1 – Task 5 (VS, KV, YÖ)
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory 6K Thymine
6L Uracil
Vicky Shingler Lecture: Scientific Literacy and the Scientific Method and Scientific article 1
assignment (VS)
14:00 - 16:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Matthew Francis Lecture: Allelic replacement in bacteria and site directed mutagenesis using PCR with introduction to computer exercise 2 (MF)
Friday2023-01-27 14:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6K Thymine
6L Uracil
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Pre-lab Experiment 1 – Task 5 and 6 (VS, KV, YÖ)
w5, 2023 
Monday2023-01-30 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Prepared discussion
6K Thymine
6L Uracil
Vicky Shingler PSC 3 and PSC 4 discussion
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Silvia Remeseiro Lecture: “Real time PCR and digital PCR” (SR)
Tuesday2023-01-31 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6K Thymine
6L Uracil
Katarina Vielfort
Yngve Östberg
Introduction to Experiment 2. “Inactivation of an E. coli gene for functional studies”, planning/discussions in groups
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Independent study Continue discussion of Exp. 2 in groups at a place of your preference.
Wednesday2023-02-01 09:30 - 15:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Prepared discussion
6L Uracil Katarina Vielfort
Yngve Östberg
Discussion of strategy for Exp. 2. (YÖ, KV)

(Group discussions: schedule will be posted after course start)
Thursday2023-02-02 08:30 - 12:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Task
6K Thymine
6L Uracil
Lecture: Yeast Genetics I, Linkage and complementation analysis in yeast. (CC) Exercise 3: “Meiotic mapping of the IMT1 gene of Saccharomyces cerevisiae and PSC 6 (questions only) (CC)
13:00 - 15:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Lecture. The CRISPR-Cas9 genome engineering system (CC)
Friday2023-02-03 13:00 - 13:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline for written report on strategy for Exp. 2 (up-load on Canvas)
w6, 2023 
Monday2023-02-06 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Lecture Canvas Johan Henriksson Lecture: Sequencing - from the past to now (JH) (pre-recorded flipped classroom).
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture Canvas Johan Henriksson Lecture: RNA-sequencing. Constructing and interpreting libraries, (JH) (pre-recorded flipped classroom).
12:00 - 16:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Task
6K Thymine
6L Uracil
Katarina Vielfort
Yngve Östberg
Exercise 2: Deletion of the nusA gene in E. coli (KV, YÖ)
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline for Experiment 1 – Task 6 written report (up-load on Canvas)
Tuesday2023-02-07 10:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Changchun Chen Lecture: Yeast Genetics II; Vectors in yeast and allelic exchange (CC)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
23:45 - 00:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline answers PSC 6 (up-load on Canvas)
Wednesday2023-02-08 08:00 - 09:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2
09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Task
6K Thymine
6L Uracil
Changchun Chen Lecture: Yeast Genetics III; Libraries and manipulation of yeast. Scientific article 2 assignment (CC)
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
Thursday2023-02-09 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Johan Henriksson Questions on lectures, Sequencing - from the past to now (JH) and RNA-sequencing. Constructing and interpreting libraries (JH)
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Prepared discussion
6K Thymine
6L Uracil
Changchun Chen Discussion PSC 6 (CC)
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Prepared discussion
6K Thymine
6L Uracil
Vicky Shingler Discussion/roundup Experiment 1 (VS)
14:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
Friday2023-02-10 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Simon Tuck Lecture: RNAi (ST)
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Anders Byström Lecture (MGA), “The wobble hypothesis revisited” (AB)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
w7, 2023 
Monday2023-02-13 08:00 - 09:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture
Mandatory
Question time
6K Thymine
6L Uracil
Jörgen Johansson Lecture: “Small RNAs”. Discovery of a new regulatory entity and PSC 7 (questions only) (JJ)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
23:45 - 00:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline answers to questions for Exp. 4 (upload on Canvas).
Tuesday2023-02-14 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Anders Byström Lecture (MGA): “The yeast Elongator complex”- genetic identification of a principle function. (AB)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 (KV, YÖ)
Wednesday2023-02-15 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Matthew Francis Lecture: Protein-protein interactions-protein based approaches (MF)
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6K Thymine
6L Uracil
Pre-lab Experiment 3; Genetic analysis of tRNA mutations (KV, YÖ)
Lecture hall: (Thymine/Uracil), thereafter Experiments 2 and 3 (red lab)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Pre-lab Experiment 3; Genetic analysis of tRNA mutations (KV, YÖ)
Lecture hall:
(Thymine/Uracil), thereafter Experiments 2 and 3 (Red lab).
Thursday2023-02-16 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiments 2 and 3
13:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Silvia Remeseiro Lecture: “Approaches to study 3D genome organization” (SR)
23:45 - 00:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline for PSC7 answers (up-load on Canvas)
Friday2023-02-17 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Changchun Chen Lecture: “Optogenetics” (CC)
10:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiments 2 and 3
13:00 - 15:00 3MB031
3MB031
5MO120
5MO120
Lecture 6A R1 Astrid Fagraeus hörsal Silvia Remeseiro Lecture (MGA): “Long-range gene regulation and 3D chromatin organization: From development to cancer” (SR)
w8, 2023 
Monday2023-02-20 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 2 and 3 (Red lab and LAB CLEANING!).
13:00 - 15:00 3MB031
3MB031
5MO120
5MO120
Lecture 6A R1 Astrid Fagraeus hörsal Jonas von Hofsten Lecture: “Fish for science; the zebrafish model system” (JvH)
Tuesday2023-02-21 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Information Student Sports Day (Hälsa på campus)
Wednesday2023-02-22 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6A R1 Astrid Fagraeus hörsal Simon Tuck Lecture: “The art of genetic screens” (ST)
Thursday2023-02-23 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture Canvas Johan Henriksson Lecture: “Analyzing NGS data with R and Linux” (JH) (pre-recorded flipped classroom).
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L J0 Vita labbet Experiment 3
Friday2023-02-24 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Prepared discussion
6K Thymine
6L Uracil
Jörgen Johansson Discussion PSC 7 (JJ)
10:15 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Changchun Chen Lecture: “Mitochondrial genetics” (CC)
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 3
w9, 2023 
Monday2023-02-27 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture Hörsal NAT.D.440 Johan Henriksson Questions on lecture “Analyzing NGS data with R and Linux” (JH)
12:00 - 14:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
6L Röda labbet
6L Röda labbet annex
Katarina Vielfort
Yngve Östberg
Experiment 3
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline for scientific article 1 written assignment.
Tuesday2023-02-28 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Information Remember to read and try to do genetic problems I for WED 1/3
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Laboratory session
Hörsal NAT.D.440 Katarina Vielfort
Yngve Östberg
Pre-lab Experiment 4: Protein-protein interactions-the 2-hybrid system - dry lab (KV, YÖ)
Wednesday2023-03-01 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Jan Larsson Lecture (MGA): “Chromosome-wide gene regulation and epigenetics” (JL)
11:00 - 11:15 3MB031
3MB031
5MO120
5MO120
Information Read and try to do genetic problems II for FRI 3/3
12:00 - 16:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Task
6K Thymine
6L Uracil
Katarina Vielfort
Vicky Shingler
Yngve Östberg
Genetic problems I (VS, KV, YÖ)
Thursday2023-03-02 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Björn Schröder Lecture: (MGA): “The human gut microbiota” (BS)
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline for the report of Exp. 2 (up-load on Canvas).
Friday2023-03-03 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Johan Henriksson Lecture (MGA): High throughput genetic screen: from behavior to molecular mechanisms. (JH)
12:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Task
6K Thymine
6L Uracil
Changchun Chen Genetic problems II (CC)
w10, 2023 
Monday2023-03-06 09:00 - 11:45 3MB031
3MB031
5MO120
5MO120
Mandatory
Redovisning
6K Thymine
6L Uracil
Changchun Chen Scientific article 1 - assessments (CC) – Completion Deadline 14.
13:45 - 14:00 3MB031
3MB031
5MO120
5MO120
Deadline Completion Deadline 14.00
14:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Lecture 6A R1 Astrid Fagraeus hörsal Johan Henriksson Lecture: “Single-cell methods with Python, and the future of molecular biology” (JH)
Tuesday2023-03-07 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline scientific article 2 written assignment (up-load on Canvas).
Wednesday2023-03-08 09:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Lecture 6K Thymine
6L Uracil
Simon Tuck Lecture (MGA): “Regulation of metabolism in the nematode C. elegans” (ST)
Thursday2023-03-09 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Redovisning
6K Thymine
6L Uracil
Changchun Chen Scientific article 2 (Groups 1-5), (CC)

In parallel, groups not discussing scientific article 2 will do Course evaluation.
10:00 - 11:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Redovisning
6K Thymine
6L Uracil
Changchun Chen Scientific article 2 (Groups 6-10), (CC)

In parallel, groups not discussing scientific article 2 will do Course evaluation.
Friday2023-03-10 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline for the report of Exp. 3 (up-load on Canvas).
w11, 2023 
Monday2023-03-13 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
16:45 - 17:00 3MB031
3MB031
5MO120
5MO120
Deadline Deadline: Report Experiment 4 (Upload on Canvas)
Tuesday2023-03-14 09:00 - 10:00 3MB031
3MB031
5MO120
5MO120
Mandatory
Prepared discussion
1D T9 Hörsal D Jörgen Johansson Discussion PSC 7 (JJ)
10:00 - 10:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
Wednesday2023-03-15 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
Thursday2023-03-16 09:30 - 12:00 3MB031
3MB031
5MO120
5MO120
Question time 6K Thymine
6L Uracil
Changchun Chen
Vicky Shingler
Questions and discussions before the exam (VS, CC)
Friday2023-03-17 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
w12, 2023 
Monday2023-03-20 09:00 - 09:15 3MB031
3MB031
5MO120
5MO120
Independent study Individual studies
Tuesday2023-03-21 09:00 - 13:00 3MB031
3MB031
5MO120
5MO120
Examination Papperstentamen U Aula Nordica Raiyan Ibrahim Aula nordica
w19, 2023 
Saturday2023-05-13 08:00 - 12:00 3MB031
3MB031
5MO120
5MO120
Examination Papperstentamen
Omtentamen
ÖP Skrivsal 4 Raiyan Ibrahim
w34, 2023 
Wednesday2023-08-23 13:00 - 17:00 3MB031
3MB031
5MO120
5MO120
Omtentamen, papper
Omtentamen
ÖP Skrivsal 5 Lina Helgesson
 
Course nameCourse code, Event code
Molecular Genetics3MB031, A3360vt23
Molecular Genetics3MB031, 33611vt23
Molecular Genetics5MO120, 51502vt23
Molecular Genetics5MO120, A5164vt23