Time
Course name
Course code
Module
Activity
Room, Location
Map link
Staff
Public comment
w17 Fri 2023-04-28 w17
09:00 - 09:30 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Information Uwe Sauer Schedule may be subject to change

Course starts. NOTE: Study free day

Course leader: Uwe Sauer
uwe.sauer@umu.se
09:00 - 09:15 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Information Text book: "Introduction to Bioinformatics 5th ed." By Arthur M. Lesk. Oxford University Press 2019, ISBN: 978-0-19-879414-1. (pp 408) ca. 538 Kr
w18 Mon 2023-05-01 w18
09:00 - 09:15 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Information Swedish holiday
  Tue 2023-05-02
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Roll-call/Introduction
6K Thymine
6L Uracil
Map
Map
Uwe Sauer Roll-call
Welcome to the course
Information and goals
Lecture: Background to the "Neanderthal K-Ras” Case study
Lesk5 Ch-1: 1-43
Lesk5 Ch-2: 48-70
Lesk5 Ch-3: 88-121
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Introduction to Bioinformatics
Serial Cloner &
Sequence alignment I: Pairwise Sequence alignments, PSA
Lesk5 Ch-4 123-135 (ex. 172)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: cont.
Sequence alignment I: Pairwise Sequence alignments, PSA
Lesk5 Ch-4 123-135 (ex. 172)
  Wed 2023-05-03
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Sequence alignment I: Pair-wise seq. alignments & "Dot plots"
Lesk5 Ch-4 123-135 (ex. 172)

Introduction PC1:
Gene finding and sequence searches
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Sequence alignment II: Substitution matrices
Lesk5 Ch-4 123-135 (ex. 172)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Sequence alignment II: Substitution matrices, E-values and scores
Lesk5 Ch-4 123-135 (ex. 172)
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC1: Sequence searches, gene finding and ORFs
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC1: Sequence searches, gene finding and ORFs
  Thu 2023-05-04
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Summary PC1

Lecture: Sequence alignment II: Substitution matrices, E-values and scores
Lesk5 Ch-4 123-135 (ex. 172)
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Sequence alignment II: Dynamic programming
Lesk5 Ch-4 137-141 (ex. 172)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Sequence alignment II: Multiple sequence alignments, MSA, visualizing alignments
Lesk5 Ch-4 143-151 (ex. 172)

Intro PC2: PSA, MSA, Patterns
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC2: PSA, MSA
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC2: PSA, MSA
  Fri 2023-05-05
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Summary PC2

Lecture: Hidden Markov Models I - theory
Lesk5 Ch-4 152-153, 171 (ex. 172)
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Hidden Markov Models II - applications
Lesk5 Ch-4 152-153, 171 (ex. 172)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Domains in proteins
Lesk5 Ch-5 190, 197-200 (ex 228)

Intro PC3 Ras structure
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC3: Ras structure
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC3: Ras structure
w19 Mon 2023-05-08 w19
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Summary PC3

Lecture: Structure superimposition
Lesk5 Ch-5 192-197 (ex 228)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Protein folding and stability: Levinthal & Anfinson
Lesk5 Ch-5 180-190 (ex. 228)

Intro PC4: Domains
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC4: Protein domains
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC4: Protein domains
  Tue 2023-05-09
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Summary PC4: Domains

Lecture: Fold recognition & Threading
Lesk5 Ch-5 205-207 (ex 228)
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Introduction to Comparative modelling
Lesk5 Ch-5 201-214 (ex 228)
Lesk5 Ch-5 215-219 (ex 228)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Comparative modelling with AI – AlphaFold 2

Intro PC5: Comparative Modeling
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC5: Comparative
Modeling
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC5: Comparative
Modeling
  Wed 2023-05-10
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Protein design; Paracelsus challenge.
Lesk5 Ch-5 197 & 213 (ex 228)
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Disordered Proteins
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Python Reviewed part 1
Lesk5 Ch-6 233-268 (ex 269)


Summary PC5 and
Tutorial: Concluding the
"Neanderthal KRas ” Case study
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC6: Python-1
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC6: Python-1
  Thu 2023-05-11
08:45 - 09:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Information NOTE: You will need to use Umeå universities VPN (virtual private network)

You also need to install “PuTTy" https://www.chiark.greenend.org.uk/~sgtatham/putty/latest.html
09:00 - 09:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Phylogenetic analysis
Lesk5 Ch-4 154-171 (ex. 172)
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Python Reviewed part 2
Lesk5 Ch-6 233-268 (ex 269)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Introduction to the Linux/Unix operating systems
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC8 Linux practical
(you will need VPN* to UmU and install “PuTTy”**)
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
PC8: Linux OS practical
Unsupervised
  Fri 2023-05-12
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: “Introduction to statistics” Patrik Ryden, PR
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: “Introduction to statistics”, PR
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC7: Python -2
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
Unsupervised
PC7: Python -2
w20 Mon 2023-05-15 w20
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: “Omics data analysis and systems biology” Nathaniel Street
Lesk5, Ch-8, 296-314 (ex. 314)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
11:30-12:00: “Omics data analysis and systems biology” Nathaniel Street
Lesk5, Ch8, 296-314 (ex. 314)
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC7: Python -2
16:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Laboratory session 6K Thymine
6L Uracil
Map
Map
PC7: Time to finish the Python labs (unsupervised)
  Tue 2023-05-16
10:00 - 10:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Artificial Intelligence (AI) – Deep Learning. Tommy Löfstedt
Lesk5 Ch-7 271-931 (ex. 293)
11:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Artificial Intelligence (AI) – Deep Learning. Tommy Löfstedt
Lesk5 Ch-7 271-931 (ex. 293)
13:00 - 13:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture on Ethics
and Bioinformatics
Lesk5, Ch-2, 80-82
14:00 - 14:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Film: GATTACA or
“Bioinformatics in the not so far future?”
15:00 - 15:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Film: GATTACA
  Wed 2023-05-17
09:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Lecture 6K Thymine
6L Uracil
Map
Map
Lecture: Next Generation Sequencing (NGS) and sequence analysis
Per Stenberg, PS
Lesk5, Ch-2, 48-79 (ex. 84)
Lesk5, Ch-3, 88-120 (ex. 121)
13:00 - 17:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Laboratory session
6K Thymine
6L Uracil
Map
Map
PC9: NGS fragment assembly and analysis. PS
You need to install student VPN on your PCs!*
  Thu 2023-05-18
09:00 - 09:15 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Information Swedish holiday
  Fri 2023-05-19
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Take-home examination
13.00 start On-Line
Take Home Exam, THE, is on-line
w21 Mon 2023-05-22 w21
09:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Take-home examination
Take Home Exam (THE)
  Tue 2023-05-23
09:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Take-home examination
Take Home Exam (THE)
  Wed 2023-05-24
09:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Take-home examination
Take Home Exam (THE)
  Thu 2023-05-25
09:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Take-home examination
Take Home Exam (THE)
  Fri 2023-05-26
09:00 - 15:45 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Take-home examination
Take Home Exam (THE)
15:45 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Mandatory
Deadline
Take-home examination
NOTE! 17.00 sharp DEADLINE for returning the THE!!
w22 Mon 2023-05-29 w22
09:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Independent study Prepare for Written Exam (WEx)
  Tue 2023-05-30
09:00 - 10:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Independent study Prepare for Written Exam (WEx)
10:00 - 12:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Question time 6K Thymine
6L Uracil
Map
Map
Question session: Last chance to ask questions before the written Exam (WEx)
13:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Independent study Prepare for Written Exam (WEx)
  Wed 2023-05-31
09:00 - 16:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Independent study Prepare for Written Exam (WEx)
  Thu 2023-06-01
08:00 - 11:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Examination Papperstentamen ÖP Skrivsal 5 Raiyan Ibrahim
w34 Fri 2023-08-25 w34
08:00 - 11:00 Bioinformatics and Genome Analysis
Bioinformatics and Genome Analysis
5MO115
5MO115
Examination Papperstentamen
Omtentamen
ÖP Skrivsal 1 Raiyan Ibrahim
 
Course codeCourse name, Event code
5MO115Bioinformatics and Genome Analysis, 51539vt23
5MO115Bioinformatics and Genome Analysis, A5159vt23