Time |
Course name |
Course code |
Module |
Activity |
Room, Location |
Map link |
Staff |
Public comment |
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| w12 | Wed 2023-03-22 w12 | ||||||||||||||||||||||||||||
| 09:00 - 09:15 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Information |
Text book: second edition:“Textbook of Structural Biology” Second edition: Release date 2016-10-01 Anders Liljas et al. World Scientific Publishing, Singapore, 2016 ISBN: 9789813142473 If you have a copy of the first edition it will also work. |
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| 09:00 - 09:45 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Roll-call/Introduction |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson |
Schedule may be subject to change Introduction to the course. Presentation of seminar and proposal topics (ESE) Course leaders: Elisabeth Sauer-Eriksson, e-mail: elisabeth.sauer-eriksson@umu.se, Uwe Sauer, Chemistry, e-mail: uwe.sauer@umu.se |
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| 10:00 - 12:30 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson |
Basics of protein structure Chapter 2, 3, 12 Protein folds (ESE) |
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| Thu 2023-03-23 | |||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
Introduction to 3D protein structure determination by different methods and Introduction to X-Ray Diffraction (XRD). Introduction to the Protein Data Bank (PDB) and the PDB file format for 3D protein structures (US) |
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| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Zoom | Elisabeth Sauer-Eriksson |
PC-lab-1 (ESE) “Introduction to ICM-Browser and RCSB – getting familial with protein structures” Zoom meeting code Liz: ID= 523-563-333 |
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| Fri 2023-03-24 | |||||||||||||||||||||||||||||
| 09:00 - 10:30 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Chapter 2, 3, 12 Protein folding and degradation (ESE) | ||||||||||||||||||||||
| 11:00 - 12:30 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer | XRD - From Crystal to Structure – Basic scattering theory (US) | ||||||||||||||||||||||
| w13 | Mon 2023-03-27 w13 | ||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD - From Crystal to Structure (1hrs) Crystallization of macromolecules, Robotics, DLS, (US) |
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| 13:00 - 17:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Laboratory session |
KB-C3-02 KB-C3-04 |
Map
Map |
Elisabeth Sauer-Eriksson | Samma labb i KB.C3.06 | ||||||||||||||||||||||
| 13:00 - 17:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Elisabeth Sauer-Eriksson Uwe Sauer |
Hall: KB-F4_XX Day 1: Setup of crystallization trials Hall: KB-F4_XX 17 students/room (13-15, and 15-17, 8 students /lab) Setting up crystallization trials (IrI, ESE, US) |
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| Tue 2023-03-28 | |||||||||||||||||||||||||||||
| 09:00 - 10:30 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Metals and cofactors in proteins (ESE) | ||||||||||||||||||||||
| 11:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD - From Crystal to Structure – Translation lattices and Symmetry (US) |
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| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Zoom | Elisabeth Sauer-Eriksson |
Zoom PC-lab 2 (ESE) “Cofactors and metals” Zoom meeting code Liz: ID= 523-563-333 |
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| Wed 2023-03-29 | |||||||||||||||||||||||||||||
| 09:00 - 12:30 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD - From Crystal to Structure – Diffraction of X-Rays by a Crystal – Bragg’s Law (US) |
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| Thu 2023-03-30 | |||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson |
Chapter 5 DNA and RNA structures (ESE) Chapter 10 Transcription and gene control (ESE) |
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| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Information | 6L Uracil | Map | room booking | |||||||||||||||||||||||
| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Zoom | Elisabeth Sauer-Eriksson |
PC-lab 3 (ESE) – “Identification of protein folds” Zoom meeting code Liz: ID= 523-563-333 |
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| Fri 2023-03-31 | |||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD – Miller Indices and Resolution in X-ray Diffraction (US) Introduction to Reciprocal Space and the Reciprocal Lattice (US) XRD – The Ewald Sphere and how to collect XRD Data (US) |
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| 13:00 - 14:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Redovisning |
6K Thymine 6L Uracil |
Map
Map |
Presentations | |||||||||||||||||||||||
| w14 | Mon 2023-04-03 w14 | ||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD – Atomic scattering factors, B-factors, XRD – Scattering by a Crystal. Intensities I(hkl) and Structure Factors F(hkl) (US) |
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| 17:45 - 18:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Deadline | Deadline for proposals at the latest 6:00 pm | |||||||||||||||||||||||||
| Tue 2023-04-04 | |||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Redovisning |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Student proposal presentations, Groups 1-8 only | ||||||||||||||||||||||
| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Redovisning |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Student proposal presentations, Groups 9-17 only | ||||||||||||||||||||||
| Wed 2023-04-05 | |||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Anders Öhman | NMR background theory (AÖ) | ||||||||||||||||||||||
| 13:00 - 15:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Anders Öhman | NMR practical (AÖ) | ||||||||||||||||||||||
| Thu 2023-04-06 | |||||||||||||||||||||||||||||
| 09:00 - 09:15 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Independent study | Canvas |
Under tiden för självstudier fram till den 16 april skall följande filmer ses - Canvas. *Film Chapter 4,13 Membrane proteins (RB) *Film Single molecules and Scanning Probe Microscope (AO) |
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| w15 | Tue 2023-04-11 w15 | ||||||||||||||||||||||||||||
| 09:00 - 09:15 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Independent study | ||||||||||||||||||||||||||
| Wed 2023-04-12 | |||||||||||||||||||||||||||||
| 09:00 - 09:15 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Independent study | ||||||||||||||||||||||||||
| Thu 2023-04-13 | |||||||||||||||||||||||||||||
| 09:00 - 09:15 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Independent study | ||||||||||||||||||||||||||
| Fri 2023-04-14 | |||||||||||||||||||||||||||||
| 09:00 - 09:15 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Independent study | ||||||||||||||||||||||||||
| w16 | Mon 2023-04-17 w16 | ||||||||||||||||||||||||||||
| 09:00 - 11:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD – the Phase Problem in Crystallography and its Solution (US) |
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| 11:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer | Bioremidation of phenols (US) | ||||||||||||||||||||||
| 13:00 - 17:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Laboratory session | KB-F4-05 | Map | Elisabeth Sauer-Eriksson | |||||||||||||||||||||||
| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Elisabeth Sauer-Eriksson Uwe Sauer |
Hall: KB-F4_XX Day 2: Inspection of crystallization trials (IrI, ESE) Demonstration of X-ray data collection facility (US) See separate schedule. |
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| Tue 2023-04-18 | |||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD – Atomic scattering factors, B-factors Calculating the Scattering from an Atom, a Molecule, a Unit Cell and from the Crystal (US) XRD – Problems and “räknestuga” (US) |
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| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Information | 6K Guanine | Map | room booking | |||||||||||||||||||||||
| 13:00 - 16:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Zoom | Elisabeth Sauer-Eriksson |
Zoom PC-lab-4 “Protein design – Case study” (ESE) Zoom meeting code Liz: ID= 523-563-333 |
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| Wed 2023-04-19 | |||||||||||||||||||||||||||||
| 09:00 - 10:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Anders Öhman | NMR in drug discovery (AÖ) | ||||||||||||||||||||||
| 10:30 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Chapter 15 Fibrious proteins (ESE) | ||||||||||||||||||||||
| 13:00 - 15:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Information | 6K Guanine | Map | room booking | |||||||||||||||||||||||
| 13:00 - 15:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Zoom | Elisabeth Sauer-Eriksson |
Zoom PC-lab-5 “Interpretation of electron density maps” (ESE) Zoom meeting code Liz: ID= 523-563-333 |
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| Thu 2023-04-20 | |||||||||||||||||||||||||||||
| 09:00 - 10:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture Question time |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson |
CRISPR/Cas from a structural perspective (ESE) + Time for questions |
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| 10:30 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Linda Sandblad Michael Hall |
Electron microscopy in Structural Studies (MH, LS) | ||||||||||||||||||||||
| 13:00 - 15:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Linda Sandblad Michael Hall |
Electron microscopy in Structural Studies (MH, LS) | ||||||||||||||||||||||
| Fri 2023-04-21 | |||||||||||||||||||||||||||||
| 09:00 - 10:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Protein Engineering (ESE) | ||||||||||||||||||||||
| 10:30 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson | Chapter 14 Signal transduction (ESE) | ||||||||||||||||||||||
| w17 | Mon 2023-04-24 w17 | ||||||||||||||||||||||||||||
| 09:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Lecture |
6K Thymine 6L Uracil |
Map
Map |
Uwe Sauer |
XRD – cont. Problems and “räknestuga” (US) XRD - Summary (US) |
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| 13:00 - 15:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Mandatory Laboratory session |
Zoom | Elisabeth Sauer-Eriksson |
Zoom PC-labs “Problems, Extra time” (ESE) Zoom meeting code Liz: ID= 523-563-333 |
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| Tue 2023-04-25 | |||||||||||||||||||||||||||||
| 10:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Question time |
6K Thymine 6L Uracil |
Map
Map |
Elisabeth Sauer-Eriksson Uwe Sauer |
Time for questions (ESE & US) | ||||||||||||||||||||||
| Thu 2023-04-27 | |||||||||||||||||||||||||||||
| 08:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Examination | Papperstentamen | ÖP Skrivsal 3 | Map | Raiyan Ibrahim | ||||||||||||||||||||||
| w34 | Tue 2023-08-22 w34 | ||||||||||||||||||||||||||||
| 08:00 - 12:00 |
Structural Biology Structural Biology |
5MO114 5MO114 |
Examination |
Papperstentamen Omtentamen |
ÖP Skrivsal 1 | Map | Raiyan Ibrahim | ||||||||||||||||||||||
| Course code | Course name, Event code |
| 5MO114 | Structural Biology, 51542vt23 |
| 5MO114 | Structural Biology, A5162vt23 |